Search results for "GENETIC OBESITY"

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MUSCLE BIOENERGETICS IN OBESE ZUCKER RATS

1994

International audience; Abstract: The purpose of this study was to investigate the energetic metabolism in obese Zucker rats, using phosphorus nuclear magnetic resonance spectroscopy at rest and during a 2-Hz muscle stimulation and subsequent recovery. Animals were anesthetized with ketamine (150 mg/kg ip). Fed obese rats and 2-day-fasted obese rats were compared with their normally fed and 2-day-fasted lean litter mates. No differences were found between the two groups for ATP, total creatine, phosphocreatine (PCr), and intracellular pH. Starvation in lean rats resulted in a significant fall in inorganic phosphate (Pi), increased resting ADP level, and decreased PCr and ADP recovery after …

medicine.medical_specialtyMagnetic Resonance SpectroscopyPhysiologyEndocrinology Diabetes and MetabolismIntracellular pHPHOSPHOCREATINE[INFO.INFO-IM] Computer Science [cs]/Medical ImagingStimulation030204 cardiovascular system & hematologyBiologyPhosphatesPhosphocreatine03 medical and health scienceschemistry.chemical_compoundAdenosine Triphosphate0302 clinical medicineMITOCHONDRIAGENETIC OBESITYPhysiology (medical)Internal medicineMUSCLESmedicine[INFO.INFO-IM]Computer Science [cs]/Medical ImagingAnimalsNUCLEAR MAGNETIC RESONANCEObesityAcidosis2. Zero hungerAnalysis of Variance[ INFO.INFO-IM ] Computer Science [cs]/Medical ImagingADENOSINE 5'-TRIPHOSPHATEADENOSINE 5'-DIPHOSPHATEMetabolismElectric StimulationRatsRats ZuckerAdenosine DiphosphateAdenosine diphosphateEndocrinologychemistryENERGETIC METABOLISMINTRACELLULAR PHFemalemedicine.symptomEnergy MetabolismAdenosine triphosphate030217 neurology & neurosurgeryMuscle ContractionMuscle contraction
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